Illustration of cannabis 280E rescheduling — Schedule III medical cannabis tax change and MSO allocation impact
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Cannabis 280E Rescheduling: Schedule III Medical Cannabis Tax Impact

What does cannabis Schedule III rescheduling mean for IRC Section 280E? The DOJ and DEA’s April 23, 2026 order rescheduling medical cannabis from Schedule I to Schedule III removes it from § 280E’s deduction prohibition — potentially cutting cannabis operators’ effective tax burden from 50-60% of operating income to closer to normal corporate rates, and…